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Imiquimod may resolve pathologic dermal fibrosis

  By Kathryn Blair  
 

Edmonton, AB--A 28-year-old Caucasian woman presented at the division of dermatology, The University of Alberta, with two plaques on the inside of her left arm. The first was 15cm by 7cm and had a slightly uneven surface with violaceous and erythematous discolouration, atrophy, and induration. The second was 5cm by 3cm, also ill-defined, pink, and atrophic. The diagnosis was cutaneous morphea.

Instead of corticosteroids, she was treated with imiquimod (Aldara) three times per week and there was an increase in erythema, induration, and size. No side effects were associated with the therapy, said Marlene T. Dytoc, MD, PhD, clinical assistant professor, division of dermatology and cutaneous sciences, University of Alberta.

 
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